Topics in Research of Physical Anthropology

2010: "Evolution of Infectious Diseases"


OBJECTIVE: To understand the current trends in studies on paleomicrobiology, mainly laying focus on ancient DNA analysis.

LECTURE in ACADEMIC YEAR 2010

Class Hours: AM 9:00-10:00 (Thu) for every lecture except for May 13 (PM 7:00-8:00); and May 21 (PM 1:00-5:00)

Location: ANATOMY ROOM #212

Credit: 3

TEXTBOOK

Emerging Pathogens by Greenblatt C and Spigelman M

SCHEDULE

Day 1: Mar 18, 2010 Chapter 1 (Handout)
*Margulis L, Dolan MF, Guerrero R. The chimeric eukaryote: origin of the nucleus from the karyomastigont in amitochondriate protists. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):6954-9. (for understanding infection and symbiosis in cell evolution)

Day 2: Mar 25, 2010 Chapter 2 to 4 (Handout)

Day 3: Apr 1, 2010: Review of Mycobacterium infection in ancient population (by Oh CS)
*Donoghue HD et al. Tuberculosis: from prehistory to Robert Koch, as revealed by ancient DNA. Lancet Infect Dis. 2004 Sep;4(9):584-92.

Day 4: Apr 15, 2010: Chapters 12 and 15 (by Oh CS)
Day 5: Apri 22, 2010: Chapters 6 and 7
Day 6: Apr 29, 2010: Chapters 8 and 9
Day 7: May 6, 2010: Chapters 10 and 11


Day 8: May 13, 2010: Special lecture: "Tomb of Akeldema and the shroud of Jerusalem" by Dr. Mark Spigelman (Editor/author of the textbook, Israel)


Day 9: May 21, 2010: Special lectures on paleoanthropology in 18th Federation Meeting of Korean Basic Medical Scientists


Day 10: June 3, 2010: Chapters 13 and 14
Day 11: June 10, 2010: Chapters 16 and 17


SELECTED PAPERS

Hershkovitz I et al. Detection and molecular characterization of 9,000-year-old Mycobacterium tuberculosis from a Neolithic settlement in the Eastern Mediterranean. PLoS One. 2008;3(10):e3426. Epub 2008 Oct 15.

Donoghue HD. Human tuberculosis--an ancient disease, as elucidated by ancient microbial biomolecules.Microbes Infect. 2009 Dec;11(14-15):1156-62. Epub 2009 Aug 29.